Coffee: Coffee can lower effectiveness and safety of levothyroxine by lowering its absorption. Grapefruit juice: Grapefruit juice can limit the absorption of
Grapefruit juice can decrease blood levels of levothyroxine, potentially decreasing the effectiveness of levothyroxine. Clinical research shows that grapefruit juice modestly decreases levothyroxine levels by 11% by inhibiting organic anion transporting polypeptide (OATP). Grapefruit juice is thought to affect OATP for only a short time.
Consuming grapefruit, grapefruit juice, or even orange juice can reduce the absorption of levothyroxine and reduce its effectiveness.
alcohol used grapefruit juice to hide the taste of the ethanol. A Levothyroxine (Eltroxin, Levoxyl, Synthroid): Grapefruit juice may slightly delay the
grapefruit juice. Conclusions Grapefruit juice may slightly delay the absorption of levothyroxine, but it seems to have only a minor effect on its bioavailability. Accordingly, the clinical relevance of the grapefruit juice-levothyroxine interaction is likely to be small. Introduction Grapefruit juice increases the plasma concentrations of
A clinically relevant interaction between grapefruit juice and levothyroxine appears unlikely.' Effects of grapefruit juice on the absorption of
Talk with your doctor about eating grapefruit or drinking grapefruit juice while you're taking Synthroid. levothyroxine alone and levothyroxine with
Do not drink grapefruit juice while taking Levothyroxine. Grapefruit juice can interfere with the absorption of Levothyroxine and impact its
The effect of grapefruit on levothyroxine is the opposite: Drinking grapefruit juice or orange juice can inhibit uptake transporters and reduce the drug s absorption.
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