Applies to: omeprazole and Integra Plus (multivitamin with iron) If you are iron-deficient or have anemia, you should talk to your doctor before using multivitamin with iron together with omeprazole. By reducing stomach acid, omeprazole may reduce the absorption of iron and make multivitamin with iron less effective in treating your condition.
[19,20] The interaction between omeprazole and iron was of moderate severity, and the mechanism was omeprazole decreases iron absorption, which requires acidic
[19,20] The interaction between omeprazole and iron was of moderate severity, and the mechanism was omeprazole decreases iron absorption, which requires acidic
Since omeprazole s effect was shown in iron-depletion or iron-overload states, it is plausible that omeprazole may have an effect on iron absorption only in abnormal iron metabolic states. Although short-term omeprazole therapy does not appear to affect iron absorption, since PPIs are increasingly being used for longer durations, further
Previous human and animal studies suggested that omeprazole may inhibit iron absorption in iron-depleted states. Two adult patients with iron deficiency anemia from erosive gastritis had their anemia corrected only after discontinuation of omeprazole . Omeprazole inhibits iron absorption in rats that were fed an iron-deficient diet .
impact on iron absorption because ferrous iron and ferric Effect of omeprazole on oral iron replacement in patients with iron deficiency anemia.
Omeprazole does not contain iron or calcium as its active ingredient is omeprazole magnesium. However, some formulations of omeprazole may contain inactive ingredients that include calcium or iron
Iron supplementation prevents the development of iron deficiency in rats with omeprazole-induced hypochlorhydria.
Our study demonstrates that short duration of omeprazole use does not affect iron absorption in iron-replete healthy individuals who are on a normal diet. Since omeprazole s effect was shown in iron-depletion or iron-overload states, it is plausible that omeprazole may have an effect on iron absorption only in abnormal iron metabolic states.
Hence Omeprazole being a much more expensive drug than it is now.....