by H Karstensen 2024Complex regional pain syndrome (CRPS). CRPS is a condition characterized with gabapentin 900 mg/day in three divided doses for CRPS type I. (n = 20)
by RN Harden 2024 Cited by 229complex regional pain syndrome (CRPS) has both fascinated and perplexed practitioners. The mechanism of action in Gabapentin may be of interest in CRPS,13. 13
There are two types of CRPS: CRPS Randomised controlled trial of gabapentin in complex regional pain syndrome type 1 [ISRCTN ].
Antiepileptic Drugs. Gabapentin is one of the most commonly prescribed pain medications for neuropathic pain in general, and in CRPS specifically. One of earliest reported uses of the drug was in a case report for the treatment of CRPS . Gabapentin is thought to work by modulating calcium channels at a specific alpha2delta subunit .
Two studies demonstrated promising preliminary evidence for an analgesic effect from gabapentin for patients with CRPS. [ 90, 91 ] A randomized, double-blind, placebo-controlled trial showed that gabapentin was mildly beneficial for pain and sensory symptoms in CRPS type I. [ 92 ] Gabapentin has been shown to be effective in treating other
Complex Regional Pain Syndrome (CRPS), sometimes also called Reflex Gabapentin – Seizure medications like gabapentin that treat neuropathic pain
In one randomized, blinded trial in 58 patients with CRPS, gabapentin had a mild effect on pain . In the largest placebo-controlled trial of gabapentin that included CRPS patients (85 of the 305 studied), gabapentin was shown to cause a significant reduction in pain, compared to placebo [ 8 ].
Gabapentin and Vitamin C to treat CRPS in Orthopaedic disorders Randomised controlled trial of gabapentin in Complex Regional Pain Syndrome
Learn about the diagnosis and treatment of CRPS, a chronic pain condition that affects the limbs. Find out how gabapentin and other medications, therapies and coping strategies can help manage CRPS symptoms.
Comments
This story is great fun; it's sexy too. I especially enjoyed the heroine/narrator's personality, including her fairly strong—but decidedly quirky—ethical principles. I do feel sorry for her uncle, though. He got left out of the action entirely. Perhaps there will be a Part 3? Fine with me, if so.
Regarding the pain in your feet, have the doctors given you a diagnosis yet or are they still looking? Also, have they considered that the pain might not originate with the feet? I spent years in a lot of pain that started in my left foot and the doctors I saw never gave me a solid answer. Just a couple of years ago, a new doctor I was seeing finally made the diagnosis. I have a very rare neuro-inflammatory disease called CRPS (Complex Regional Pain Syndrome) which can affect any limb and often spreads over time. Once I knew and was able to start learning more, it helped me so much to understand what was causing the pain and find at least some things I could do to help reduce it. Although there is no known cure for CRPS, and the disease continues to advance as I get older, it has at least given me a starting point for research and trying to understand.
Having to live with any type of chronic pain is something that is so difficult to truly understand for people who have never experienced it and while I am not bi-polar, I have had to start taking meds for depression (and I was already on meds for ADHD and anxiety). I greatly sympathize with the things you have been through and truly hope that things are getting better. You have incredible talent and I would love to see you feeling better and able to share more of your great stories as you can.
Not much good news. Went to my neuropathist on Wednesday for a series of tests. 'Yes', I have nerve damage and 'no', the doctor looking at the results couldn't understand why. Essentially, they ran an escalating electric current from various spots on my lower leg and foot to toes to see how I responded. I highly recommend this as a means of torture.
On the downside, I am becoming resistant to my pain medication, so life sucks coming and going. My psychiatrist upped my Gabapentin from 300 Mg to 400 Mg [3x a day] and it isn't helping. Woot? I'd kill for a decent night's sleep.
Thank you for asking. I really wish I had better news.
James aka FinalStand
Also Ellie, I second Gypsy's suggestion that you might take on a story with a disabled character in it. Preferably a female one. I would never feel comfortable suggesting it to another writer but I think you would be able to do it justice. If you and wanted some insight to chronic illness I would be happy to help.
I'm also going to look up the naked gardener as well. Thanks for the tip. :)
On the beneficial side, I know where I want to take Chapter 5 in this tale. I have much of it mapped out in my mind.
They travel to the mainland in pursuit of the Atlanteans ... which completes the 13th Circle of the Black Witches Coven (whoops!) ~ giving the descendants of the other 7 the power they have been long denied. There is still the government task force on the serial killings to deal with plus the on-going conflict with the White Coven. The main mystery remains ~ what was an Atlantean doing breeding with an Abenaki and teaching at least one half-breed offspring magic over 400 years ago ... and why would a normally amoral Altantean 'noble' be interested in said half-breed today?
God - sometimes I really wish I had a clone ... or two.
James aka FinalStand
As for everyone else ... life keeps adding on the 'happy' {sarcasm}.
My neurologist decided to prescribe a more powerful tool to manage the pain in my feet. So, he gave me a foot cream. What wasn't obvious was the non-prescribed 'side effects' of the foot cream which included ... (sigh) ...
Well, as my feet have been hurting like sons-a-bitches, I was slathering that cream on three and four times a day. It had minimal positive effect which was leagues ahead of the pain I was going through. Besides, it was foot cream. What was the worse that could happen?
Baclofen (2%) ~ [Lightheadedness or fainting, trouble seeing, severe tiredness, weakness],
Cyclobenzaprine (2%) ~ [Anxiety, restlessness, seeing or hearing things that are not there, severe drowsiness, fainting, or confusion],
Diclofenac (3%) ~ [Sudden or severe headache, or problems with vision, speech, or walking],
Gabapentin (6%) ~ [Behavior problems, aggression, restlessness, trouble concentrating, moodiness (especially in children), problems with coordination, shakiness, unsteadiness, unusual moods, or behaviors, thoughts of hurting yourself, feeling depressed, dizziness, drowsiness, sleepiness, tiredness],
Lidocaine (2%) ~ [which, somewhat stunningly, isn't trying to fuck with my head]
So I've been staggering around in a semi-lucid state for the past several days, unable to figure out why I couldn't do much, if any, writing. It took me complaining to my wife to provide some clarity.
I repeat - it is freaking foot cream!
I've stopped with the foot-crack and am back to dealing with the pain. Hopefully I'll be back to writing soon too.
James aka FinalStand