Niacin is the most potent available drug in increasing HDL-C levels (up to 30%), but its use is limited by side effects, especially flushing.The present chapter reviews the effects of established hypolipidemic drugs (statins, fibrates, and niacin) on plasma HDL-C levels and HDL subclass distribution, and on HDL functions, including cholesterol
There are several basic mechanisms by which a drug can raise HDL cholesterol: an increase in the uptake of cholesterol from tissues by HDLs; an increase in the transfer of cholesterol from other lipoproteins to HDLs; a reduction of the rate of transfer of cholesteryl esters from HDLs to the liver; and a reduction of cholesteryl ester transfer
decrease LDL (bad) cholesterol and triglyceride levels. increase HDL (good) cholesterol levels. decrease the Total Cholesterol/HDL-Cholesterol Ratio (TC: HDL-C
decrease LDL (bad) cholesterol and triglyceride levels. increase HDL (good) cholesterol levels. decrease the Total Cholesterol/HDL-Cholesterol Ratio (TC: HDL-C
by A Scriabine 2024Atorvastatin may increase HDL particles by decreasing activity of cholesteryl ester transfer protein (CETP). Inhibitors of CETP are expected to increase. HDL
However, low levels of HDL cholesterol have not been established as causative of this increase in risk. (See 'Low HDL cholesterol as an ASCVD risk factor' below and 'Effect of increasing HDL cholesterol on clinical outcome' below.) This topic will address clinical aspects of abnormal HDL (the particle) and HDL cholesterol.
Rosuvastatin is an oral drug for lowering blood cholesterol levels. Rosuvastatin is used for the reduction of blood total cholesterol, HDL cholesterol, and triglyceride levels, and to increase HDL cholesterol levels.
Niacin has been promoted for decades as a high-density lipoprotein (HDL)-raising drug. It does increase HDL cholesterol (HDL-C) by reducing the number of small
decrease LDL (bad) cholesterol and triglyceride levels. increase HDL (good) cholesterol levels. decrease the Total Cholesterol/HDL-Cholesterol Ratio (TC: HDL-C
Isaac Asimov’s Three Laws of Robots does not apply here. Lots of possibilities.
Howard Campbell could be named after John W. Campbell who shaped sci-fi for the readers’ enjoyment.
Shame on HDL for not providing a sequel for his readers. Not nice to leave them hanging.
The story has a single focus. Expand the scope with subplots which become plots.
HDL, rewrite, edit and polish your story and sequel.
That’s how Sci-Fi Grandmasters are thusly honored by their works.
Best of luck in your endeavors.