Cardiotoxic chemotherapy drugs

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Actual: While antimicrotubular agents such as the taxanes cause cardiotoxicities that include heart block, hypertension, arrythmias, and CHF, recent study of taxane cardiotoxicity has explored if they exacerbate toxicity of other chemotherapy drugs such as anthracyclines or trastuzumab [2,30].
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Unfortunately, anthracyclines are considered the principal culprit drugs behind chemotherapy-induced cardiotoxicity (1 5). The pathognomonic manifestation of anthracycline-induced cardiotoxicity is a hypokinetic cardiomyopathy progressively leading to heart failure, first described in 2024 ( 6 ).

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drug information for this topic. No drug references cardiotoxicity - Left ventricular dysfunction associated with chemotherapy drugs

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Moslehi continued, referring to the commonly used chemotherapy drug that has been the focus of much cardiotoxicity research over the past decade

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DEFINITION OF CHEMOTERAPY-INDUCED CARDIOTOXICITY. Cardiotoxicity is a general term used to define toxicity that affects the heart ().A growing body of researches is now studying cardiovascular events associated with chemotherapy (), however a clear definition of cardiotoxicity and the certain mechanisms involved are lacking.

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(See Cardiotoxicity of cancer chemotherapy agents other than ○Exposure to other cardiotoxic cancer therapies – Other cancer

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by TWM Jr Cited by 42Am J Cancer Res 2024;11(4): . Table 1. List of chemotherapy agents which cause cardiotoxicity. Serial No. Agent. Cardiotoxic Effect.

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Definition of Chemotherapy Induced Cardiotoxicity Defined traditionally as a decrease in LVEF due to chemotherapy PREDICT Trial Effectiveness of Using Biomarkers to Detect and Identify Cardiotoxicity and Describe Treatment Cardiotoxicity defined as presentation of one or more cardiac events within 12 months of initiation of chemotherapy

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Cardiotoxicity is heart damage caused by cancer treatment. It may develop after radiation therapy to the chest or taking certain chemotherapy drugs.

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anthracycline-based cancer pharmacology is suggested. Chemotherapy-Induced Cardiotoxicity Cardiac toxicity: old and new issues in anti-cancer drugs.

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