Baclofen does lower the seizure threshold so I wouldn't advise you to take it with tramadol under any circumstances.
Baclofen does lower the seizure threshold so I wouldn't advise you to take it with tramadol under any circumstances.
Even if constipation is well managed, baclofen may disrupt this management, thus limiting titration to an effective dose. Lastly, with regard to the effect of baclofen on seizures, studies are mixed regarding baclofen lowering a person s seizure threshold, causing new onset seizures, or exacerbating an existing seizure disorder . For children
Also report the use of drugs which might increase seizure risk (decrease seizure threshold) when combined with baclofen such as isoniazid (INH)
Additionally, medications that lower the seizure threshold, such as seizures in patients taking baclofen. In conclusion, baclofen
by JE Brandenburg 2024 Cited by 3Lastly, with regard to the effect of baclofen on seizures, studies are mixed regarding baclofen lowering a person's seizure threshold, causing
Interaction Characteristics: CNS depression; lowers seizure threshold. Avoid/Use Alternative. aldesleukin. 1 interaction. baclofen (generic).
by SR Holt Cited by 4Intractable vomiting may lead to electrolyte abnormalities which may lower the seizure threshold. Baclofen – Baclofen is another option for treatment
Baclofen is metabolized by the liver and eliminated by renal excretion. Because baclofen readily crosses the blood-brain barrier, sedation, fatigue, dizziness, lowering of the seizure threshold
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