by J Wang 2024 Cited by 26Ibuprofen induced significant decreases in OA in CML samples and healthy donors. Conclusion: On the basis of the expected impact of these two drugs on OA
X-ray image of knees with osteoarthritis. What is osteoarthritis (OA)?; OA vs. rheumatoid arthritis; OA symptoms; Diagnosing OA; OA treatments
Pain relief is the main indication for drug treatment in patients with OA, most OA patients visit a doctor for their pain treatment. 4,5 Clinical trial data show that the traditional nonsteroidal antiinflammatory drugs (NSAIDs) are more effective than acetaminophen in the treatment of patients with symptoms and signs of OA. 6,7 However, NSAIDs
Osteoarthritis (OA) is a very common and severely debilitating disease with an unmet medical need, and new drugs are needed to alleviate OA symptoms and/or prevent structural progression.
by GY Oh 2024The prevalence of gabapentin use, concurrent use of gabapentin with opioid analgesics (OAs) (gabapentin-OA), and gabapentin with OAs and
Osteoarthritis (OA) is a painful and disabling disease that affects millions of people worldwide. Symptom-alleviating treatments exist, although none with long-term efficacy. Furthermore, there are currently no disease-modifying OA drugs (DMOADs) with demonstrated efficacy in OA patients, which is
Despite a high burden of disease there are no approved disease-modifying OA drugs (DMOAD) and current strategies for pain relief are inadequate. Eventually many patients progress to late-stage OA
by EC Rodriguez-Merchan 2024 Cited by 24Disease-modifying OA drugs (DMOADs) could offer new therapeutic targets aimed at restoring the quality and function of tissues affected by OA.
Osteoarthritis (OA) is a chronic degenerative disease of the joints. The latest OA management guidelines commonly suggest non-steroidal anti-inflammatory drugs
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