Colitis clindamycin
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5.1 Colitis. Systemic absorption of clindamycin has been demonstrated following topical use. Diarrhea, bloody diarrhea, and colitis (including pseudomembranous colitis) have been reported with the use of topical clindamycin.
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Clindamycin and colitis/intestinal microflora. Due to the association with pseudomembranous or C. difficile colitis, oral clindamycin should be prescribed with caution in patients with a history of colitis or GI disease (Table 1) (Citation 9). Though the association with topical clindamycin formulations is less clear (Citation 24).
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Systemic absorption of clindamycin has been demonstrated following topical use of clindamycin. Diarrhea, bloody diarrhea, and colitis (including pseudomembranous colitis) have been reported with the use of topical and systemic clindamycin.
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Colitis: Clindamycin can cause severe colitis, which may result in death. Diarrhea, bloody diarrhea, and colitis (including pseudomembranous colitis) have been reported with the use of clindamycin. Clindamycin Phosphate and Benzoyl Peroxide Gel, 1.2%/5% should be discontinued if significant diarrhea occurs.
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Clindamycin (Cleocin); Fluoroquinolones (Cipro, Levaquin); Penicillin Ulcerative Colitis Reference Ulcerative Colitis Slideshows
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Orally administered and injected clindamycin may cause severe colitis. Orally or injected clindamycin have been associated with severe colitis which may result
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History of regional enteritis, ulcerative colitis, or antibiotic-associated colitis Colitis: Clindamycin can cause severe colitis, which may result in
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Colitis: Clindamycin can cause severe colitis, which may result in death. acnes resistance to clindamycin in the treatment of acne. In patients with P
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Clindamycin Phosphate Topical Solution, Clindamycin Phosphate Gel, and Clindamycin Phosphate Lotion are contraindicated in individuals with a history of hypersensitivity to preparations containing clindamycin or lincomycin, a history of regional enteritis or ulcerative colitis, or a history of antibiotic-associated colitis.
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