The patient was only temporarily responsive to IV metoprolol and wasn't responsive whatsoever to PO metoprolol tartrate or PO amiodarone. I
3. Amiodarone pharmacology. Loading with amiodarone can be done in several ways IV, PO, IV followed by PO, or IV and PO together. The loading regimen employed depends on the clinical indication and the rapidity of effect desired. More rapid loading slightly increases the risk of acute side effects.
IV to PO conversion of Amiodarone after 48 hours. Special Instructions: If the patient is taking other PO meds then stop the infusion and order 400 mg PO bid.
The only information that I could find about PO to IV conversion involved patients who are stabilized on amiodarone PO for 4 months or longer. Because a typical oral amiodarone loading dose
afib or ≥2 failed attempts to wean from IV amiodarone. ▫ ≤ 24hours on IV amiodarone: start mg po Q12h. ▫ ≥ 48hours on IV amiodarone: start 200mg po q12h.
afib or ≥2 failed attempts to wean from IV amiodarone. ▫ ≤ 24hours on IV amiodarone: start mg po Q12h. ▫ ≥ 48hours on IV amiodarone: start 200mg po q12h.
by U Khanderia 2024 Cited by 19May start amiodarone IV or PO. 6. Amiodarone 150 mg IV bolus (may repeat). 7 PO: 600 mg PO TID x 9 doses, then 200 mg PO daily. FIG. 1 Management and
PO amiodarone 25.7 mg/kg vs. IV amiodarone 3-5 mg/kg bolus then mg/kg over 24 h. No difference in conversion to SR between PO and IV.
IV, intravenous; PO, oral; SR, sinus rhythm. Eur Heart J. 2024 Oct;15 PO amiodarone 25.7 mg/kg vs. IV amiodarone 3-5 mg/kg bolus
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Boyd