Pegfilgrastim vs filgrastim

Related drugs Filgrastim Lenograstim Lipegfilgrastim Pegfilgrastim.

Take medications filgrastim (Neupogen) tbo-filgrastim (Granix) pegfilgrastim (Neulasta) eflapegrastim (Rolvedon).

The prescribing information for Neulasta, Fulphila, Fylnetra, Nyvepria, Stimufend, Udenyca, and pegfilgrastim 6 mg, pegfilgrastim 12 mg and filgrastim groups.

Compare Filgrastim vs Pegfilgrastim head-to-head with other drugs for uses, ratings, cost, side effects and interactions.

Results: Medical records of 624 pts from 34 sites receiving pegfilgrastim or filgrastim have been abstracted to date. Pegfilgrastim was initiated in 351(56%) pts and filgrastim was initiated in 273 (44%) pts. Of the 624 pts, 120 (19%) received both pegfilgrastim and filgrastim (no pt used both products in the same cycle).

In Skarlos et al, a post-hoc non-randomized subgroup analysis evaluating filgrastim versus pegfilgrastim, a significantly higher incidence of FN was observed in patients treated with pegfilgrastim compared with those receiving filgrastim (13% vs. 1% for pegfilgrastim vs. filgrastim, respectively) .

Other treatment-related adverse events including arthralgia (1.7 vs 6%), back pain (6.9 vs 3%) and headache (1.7 vs 6%) were reported for pegfilgrastim vs filgrastim.

Granix (tbo-filgrastim) ; Neulasta (pegfilgrastim) ; Neupogen (filgrastim).

Prophylaxis with pegfilgrastim was significantly associated with lower FN-related chemotherapy disruption rates (8.3 vs 17.3% in the pegfilgrastim and filgrastim groups, respectively) and fewer FN-related days in hospital (0 vs 15 days, respectively).