Baclofen toxicity in kidney disease Nephpearls
Physicians should consider baclofen toxicity in patients with suboptimal kidney function on baclofen who present with altered mental status.
Some experts recommend giving a lower baclofen dosage for people with mild to moderate kidney disease (stage 2 or 3) and avoiding baclofen completely in people with more severe kidney disease (stage 4 or 5). So if you have existing kidney problems, let your healthcare provider know before starting baclofen.
by O Malle 2024It is contraindicated in chronic kidney disease. As it is eliminated predominantly by the kidneys, acute kidney injury can lead to acute baclofen overdose with
If you have kidney problems or a history of kidney disease, your kidney baclofen during pregnancy. You should not discontinue baclofen
by O Malle 2024It is contraindicated in chronic kidney disease. As it is eliminated predominantly by the kidneys, acute kidney injury can lead to acute baclofen overdose with
Since baclofen is largely eliminated by the kidneys, a dosage reduction is advised to avoid drug accumulation. Baclofen should be used with caution in patients
baclofen in patients with renal insufficiency. Thus, many baclofen withdrawal syndrome after kidney transplant. 42 yo with HTN
BACLOFEN Intrathecal (baclofen injection) is indicated for the other drugs which affect the kidney, e.g. ibuprofen. opiates for
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