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Bexacat is the first sodium-glucose cotransporter 2 (SGLT2) inhibitor approved by the FDA in any animal species. Bexacat introduces a new

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Treatment with Bexacat may increase the risk for urinary tract infections (see Adverse Reactions). Cats treated with Bexacat should be monitored for urinary tract infections and treated promptly. Consider discontinuation of Bexacat in cats with recurrent urinary tract infections. Bexacat may cause increased serum calcium concentrations.

Bexacat is a sodium-glucose cotransporter 2 (SGLT2) inhibitor. SGLT2 is the primary transporter responsible for reabsorption of glucose from the glomerular filtrate back into the circulation. By inhibiting SGLT2, Bexacat reduces renal reabsorption of filtered glucose and lowers the renal threshold for glucose, increasing urinary glucose excretion.