Dosage of voriconazole

Administration of a higher voriconazole dose (400 mg every 12 hours x 7 days) with phenytoin (300 mg once daily) resulted in comparable steady state voriconazole C max and AUC estimates as compared to when voriconazole was given at 200 mg every 12 hours without phenytoin [see Dosage and Administration ( 2.7) and Drug Interactions ( 7)] .

prednisone 10mg dosage instructions. Details. Voriconazole: moderate leukopenia, neutropenia, anemia, and when reduction in edema or scar tissue

Voriconazole for injection may increase the concentrations and activity of drugs that are CYP3A4, CYP2C9 and CYP2C19 substrates. Reduce dosage of these other drugs and monitor for adverse reactions (4, 7) Phenytoin or Efavirenz: With co-administration, increase maintenance intravenous dosage of Voriconazole for injection (2.3, 2.7, 7)

There was no significant pharmacokinetic interaction between fluconazole and azithromycin. Voriconazole: Voriconazole is a substrate for both CYP2C9 and CYP3A4

↓ voriconazole. ↑ ketoconazole. ↑ isavuconazonium sulfate. ↑ itraconazole Dosage adjustment of cilostazol is recommended. Refer to the cilostazol

There was no significant pharmacokinetic interaction between fluconazole and azithromycin. Voriconazole: Voriconazole is a substrate for both CYP2C9 and CYP3A4

There was no significant pharmacokinetic interaction between fluconazole and azithromycin. Voriconazole: Voriconazole is a substrate for both CYP2C9 and CYP3A4

voriconazole, a commonly used azole. - The emergence of azole The widespread availability of low-dosage, over-the-counter

Dosage Modifications. Renal impairment. CrCl 90 mL/min and aged 60 yr: q8hr Interaction mainly occurs in preterm infants. voriconazole. voriconazole