Kd drugs

☑️@kd_drugs · 5787 subscribers · Content 18+ 🔞
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Kd of the drug refers to the concentration at which fractional occupancy of binding sites by drug molecules is 50%.

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Kd measures how tightly a drug binds to its receptor. Kd is defined as the ratio of rate constants for association (kon) and dissociation (koff) of the drug to and from the receptors. At equilibrium, the rate of receptor-drug complex formation is equal to the rate of dissociation into its components receptor drug.

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