Amlodipine and statins interaction

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Actual: Amlodipine increases the AUC of both statins Evaluating the Landscape of Statin Drug Interactions with Select Cardiovascular Medications: What
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Pharmacokinetic data suggest a minor increase in statin exposure with coadministration of amlodipine and lovastatin or simvastatin, and combination therapy may be considered. There is no evidence of significant interaction when amlodipine is coadministered with other statins.

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Examples of statins include atorvastatin (Lipitor) amlodipine (Norvasc); ranolazine (Ranexa). Another important drug interaction occurs between statins

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reported, but none with a simvastatin-amlodipine interaction. [16, 17] gerous interactions of some statins (simvastatin) with drugs.

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amlodipine which were not observed with simvastatin 20 mg plus amlodipine. Statins: interactions, and updated advice for atorvastatin

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‐ statin drug‐interaction with amlodipine. Simvastatin, oral. Dose amended. ‐ myalgia associated with statins. HMGCoA reductase inhibitors. (statins), oral.

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Curiously, the adverse effect rate of the statin, it is always very similar to that of placebo. drug interactions e.g. amlodipine and statins.

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Pharmacokinetic data suggest a minor increase in statin exposure with coadministration of amlodipine and lovastatin or simvastatin, and combination therapy may be considered. There is no evidence of significant interaction when amlodipine is coadministered with other statins.

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Some medications may interact with statins by decreasing the effectiveness of the statin. Norvasc (amlodipine); Lanoxin (digoxin); Cardizem (

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reported, but none with a simvastatin-amlodipine interaction. [16, 17] gerous interactions of some statins (simvastatin) with drugs.

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