Anti angiogenic drugs
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action of dierent anti-angiogenic drugs, the combination therapy of anti-angiogenic drugs and other anti-tumor drugs, and the mechanism of anti-angiogenic drug resistance. Keywords Lung cancer Angiogenesis Anti-angiogenic drugs Combination therapy Drug resistance Introduction Based on the results of two phase III trials (ECOG4599
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by ZL Liu 2024 Cited by 249inhibitors are the mainstream drugs used in anti-angiogenic treatment. Inhibitors approved for anti-angiogenic therapy are summarized in
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Inhibiting angiogenesis requires treatment with anti-angiogenic factors, or drugs which reduce the production of pro-angiogenic factors, prevent them binding to their receptors or block their actions.
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However, anti-angiogenic therapy can normalize tumor vessels by interfering the interaction between VEGF and VEGFR or disturbing the angiogenic signaling. 18 So far, numerous anti-angiogenic drugs have been developed to treat various cancers, all of which can be classified into 4 types: (1) anti-VEGF monoclonal antibody (mAb); (2) anti-VEGFR
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Background: There is a large amount of evidence that anti-angiogenic drugs are effective safe. However, few studies have evaluated the specific effects of anti-angiogenic drugs on myocardial enzyme injury biomarkers: aspartate aminotransferase (AST)
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Anti-angiogenic drugs can act as decoy agents, monoclonal antibodies, or tyrosine kinase inhibitors. Bevacizumab was the first anti-angiogenic drug approved for human use, however, its use as monotherapy is inefficient.
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The discovery of pathways mediating tumor angiogenesis, in particular VEGFs and their receptors, paved the way to the development of anti-angiogenic drugs to translate into clinic as anti-cancer agents. However, dozens of anti-angiogenic drugs have been approved and routinely used under clinical practice.
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Endothelial function as an anti-angiogenic drug biomarker: Version 1 Anti-angiogenic drugs suppress the growth of new blood vessels. Because of
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by S Frandsen 2024 Cited by 26Methods: This paper reviews four relevant anti-angiogenic drugs: bevacizumab, ramucirumab, nintedanib and sunitinib. anti-angiogenic drugs in
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Thanks for sharing, Tess (uk)