Fosphenytoin vs phenytoin

Fosphenytoin displaces phenytoin from protein binding sites. The volume of distribution of fosphenytoin increases with fosphenytoin sodium injection dose and rate, and ranges from 4.3 to 10.8 liters. Elimination. The conversion half-life of fosphenytoin to phenytoin is approximately 15 minutes. Metabolism

Fosphenytoin vs phenytoin for acute treabnent of seizures. A US study demonstrated a cost saving with the use of IV fosphenytoin versus IV phenytoin in the.

Phenytoin vs Fosphenytoin Phenytoin and fosphenytoin have sodium channel blockade effects, which is similar to the mechanism of action of

vs 11% of IM placebo-treated patients hypoalbuminemia, fosphenytoin clearance to phenytoin may be increased without a similar increase in phenytoin clearance.

Comparing Fosphenytoin vs Phenytoin ; Be the first to share your experience with this drug. Phenytoin has an average rating of 7.5 out of 10 from a total of 112

phenytoin equivalents (PE) (1mg PE Fosphenytoin = 1 mg IV phenytoin); 42. Phenytoin vs Fosphenytoin Phenytoin Fosphenytoin Vehicle Propylene

by X Li 2024Intravenous and intramuscular administration of fosphenytoin sodium causes rapid and complete conversion of fosphenytoin to phenytoin, with a

Dose equivalence and conversion for fosphenytoin sodium Doses are expressed as phenytoin sodium equivalent (PE); fosphenytoin sodium 1.5 mg ≡ phenytoin sodium

This results in slow and erratic absorption (7, 10). Like phenytoin, fosphenytoin binds extensively to albumin. It displaces any lingering phenytoin from plasma protein bindBUMC PROCEEDINGS 2024; JULY 2024 PHENYTOIN VS FOSPHENYTOIN ing sites, increasing up to 30% the unbound phenytoin fraction available for antiepileptic activity.