Celecoxib half life

Other celecoxib brands include: Elyxyb Cambia, Cataflam, Lofena, Voltaren, Zipsor, Zorvolex Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

Half-life 11 hours under fasting conditions. Mean apparent elimination half-life approximately 6 hours, independent of dosing conditions, when administered as oral solution; half-life similar to that observed for celecoxib capsules under fed conditions.

Sulindac (half-life approx. hours): 4 days (based on active metabolite) Tenoxicam (half-life 72 hours): 15 days COX-2 selective inhibitors (e.g. celecoxib

2.3. Classification of NSAIDs on the basis of plasma half-life (t ) NSAIDs can also be divided into short-acting (plasma half-life less than 6 h) such as aspirin, diclofenac and ibuprofen and long-acting (half-life approximately greater than 10 h) such as naproxen, celecoxib.

Celecoxib-Tramadol is a combination medication Coadministration increases digoxin serum concentration and prolongs digoxin half-life.

Celecoxib has a half-life of about 11 hours. A drug's half-life is the length of time it takes for half a dose of the drug to be removed

Introduce celecoxib at half the recommended dose in arthritis or pain patients with moderate hepatic After multiple dosing, elimination half-life is 8 to12

The effective half-life of celecoxib is approximately 11 hours when a single 200 mg dose is given to healthy subjects. 25,31 The terminal half-life of celecoxib varies because of its low solubility, which prolongs absorption. 31

Orally administered celecoxib exhibits good systemic bioavailability and tissue distribution with an estimated plasma half-life of approximately 11 h. Celecoxib