drugs. Depression is common among people with HIV and there is some integrase inhibitors (INI, INSTI). A class of antiretroviral
No resistance to the Cabotegravir (or other integrase inhibitor [INSTI] drugs) drugs – again to reduce the risk of developing drug resistance
by M Sayan 2024 Cited by 12Objectives: Integrase strand transfer inhibitor (INSTI) is a new class of antiretroviral (ARV) drugs designed to INSTI resistance mutations in Turkish
Therefore, it is not anticipated that they will be used with oral NNRTIs or PIs. ARV Drugs by Drug Class. INSTIs. BIC. DTG. EVG/c.
by C Spitznagel 2024well as individual INSTI drugs. We compared the proportion of women with viral suppression at delivery between INSTIs and non-INSTIs as well between
Advantages of these INSTIs include their high genetic barrier to resistance, limited drug-drug interactions, excellent rates of virologic suppression, and favorable tolerability. Few INSTI resistance-associated mutations have been reported in clinical trials involving dolutegravir, bictegravir and cabotegravir.
by BN Harding 2024 Cited by 7These findings suggest INSTI use may increase the risk of anaemia. If confirmed, screening for anaemia development in users of INSTIs may be beneficial.
by M Li 2024 Cited by 22drugs, the IN strand transfer inhibitors (INSTIs). Collectively, these changes weaken chelation of the bound INSTI, leading to a reduction in
by SK Sayyed 2024 Cited by 2The first INSTI to get approved was raltegravir (RAL) in 2024 as a therapeutic INSTI by the US Food and Drug Administration (FDA), followed by
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