Drugs that cause hyponatremia

Hyponatremia Induced by Drugs Medications make up one of the most frequent causes of hyponatremia. They may induce hyponatremia by affecting either the sodium

Carbamazepine often causes drug-induced hyponatremia. Hyponatremia due to carbamazepine may be improved by changing to the same mechanism of

Diuretics such as furosemide may cause hypovolemic hyponatremia. Other medications that cause hyponatremia include theophylline, carbamazepine, chlorpromazine, indapamide, amiodarone, and selective serotonin reuptake inhibitors. Most of these cause SIADH (euvolemic hyponatremia). Morphine and barbiturates can also cause hyponatremia.

keep amlodipine in mind as a rare cause of drug induced hyponatremia and to especially consider this medication as a cause of chronic hyponatremia in the elderly population.

Background: Hyponatremia is the most common electrolyte disorder. Thiazides, antidepressants, antipsychotic drugs, and antiepileptic drugs are well-known causes of hyponatremia.

This review in AJKD lists most of the causes of drug-induced hyponatremia and provides the rationale for why hyponatremia occurs in the setting of these drugs.

by KP GOH 2024 Cited by 250Medications and drugs that cause hyponatremia are listed in Table 1. Some of the more common causes of medication-induced hyponatremia are

cause of drug-induced hyponatremia.1,2 Thiazide-associated hyponatremia most arvense (because this medication contributed to hyponatremia), and amlodipine (

Isotonic hyponatremia (pseudohyponatremia). Normal. ↑, Normal Stop all medications that may be causing hyponatremia. If the cause