Using the sponsor submitted price for cabozantinib and publicly listed prices for all other drug costs, the incremental cost-effectiveness ratio (ICER) for cabozantinib plus best supportive care (BSC) was $664,742 per quality-adjusted life-year (QALY) compared with BSC alone.
Cabometyx (cabozantinib) is a prescription drug that's used to treat certain types of cancer. Cabometyx's cost may depend on factors such as
Only direct medical costs were considered, including costs for cabozantinib, computed tomography, and management of grade 3-4 AEs (Table 1). The US cost of cabozantinib using the average wholesale price (AWP) in the Red Book,[19] was $10.93 per mg, the UK cost was $4.04 per mg,[20] and the
cabozantinib group gains 1.19 QALYs, resulting the ICER was 288 443.23 USD per QALY. One-way sensitivity analysis suggested the cost of nivolumab, the discount rate, and the cost of cabozantinib had a great impact on the ICER. The cost-effectiveness acceptability curves showed the probability of nivolumab plus cabozantinib being cost-effective
The total mean cost per patient was $56,621 for cabozantinib and $2024 for best supportive care in the German model resulting in incremental cost-effectiveness
When quality of life was incorporated, treatment with cabozantinib produced a gain of 0.16 QALYs. The total mean incremental cost of cabozantinib was US$76,406 per patient. The incremental cost-effectiveness ratio for cabozantinib compared with best supportive care was US$469,374/QALY using the recommended dose of 60 mg cabozantinib daily.
Nivolumab Cabozantinib. Nivolumab request for information where the cost of compliance is estimated to exceed the appropriate limit.
The majority of incremental cost for cabozantinib was from the medicine acquisition costs. 6.3. Sensitivity analyses. The scenario analyses
The total mean cost per patient was $56,621 for cabozantinib and $2024 for best supportive care in the German model resulting in incremental cost-effectiveness ratios for cabozantinib of $306,778
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Lack of a cuckold tag cost you. - perhaps someday something so insignificant will cost you as well.
But... what is the cost? There will be a downside, or cost of some kind, and it will be a Doozie!