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Author: Admin | 2025-04-28
ML vehicle to provide a total of 75 mL. Treatment dose is 5 mL (30 mg) twice daily for 5 days. Prophylactic dose is 5 mL (30 mg) once daily for 10 days.16 to 23 kg: To make a 6 mg/mL suspension, open eight 75 mg capsules. Mix with 7 mL water and 91 mL vehicle to provide a total of 100 mL. Treatment dose is 7.5 mL (45 mg) twice daily for 5 days. Prophylactic dose is 7.5 mL (45 mg) once daily for 10 days.24 to 40 kg: To make a 6 mg/mL suspension, open ten 75 mg capsules. Mix with 8 mL water and 115 mL vehicle to provide a total of 125 mL. Treatment dose is 10 mL (60 mg) twice daily for 5 days. Prophylactic dose is 10 mL (60 mg) once daily for 10 days.≥41 kg: To make a 6 mg/mL suspension, open twelve 75 mg capsules. Mix with 10 mL water and 137 mL vehicle to provide a total of 150 mL. Treatment dose is 12.5 mL (75 mg) twice daily for 5 days. Prophylactic dose is 12.5 mL (75 mg) once daily for 10 days.Alternate recommendations (Tamiflu Canadian product labeling 2017):Preparation of Oseltamivir 6 mg/mL Suspension: (using water with preservative [ie, 0.05% sodium benzoate])Body WeightTotal Volume per Patient1# of 75 mg Capsules2Required Volume of Water (with preservative)Treatment Dose (wt based)2,3Prophylactic Dose (wt based)2,31Entire course of therapy.2Using 6 mg/mL suspension.3Measured dose should be mixed with an equal amount of sweetened liquid (eg, chocolate syrup, cherry syrup) to mask bitter taste.≤15 kg75 mL674 mL5 mL (30 mg) twice daily for 5 days5 mL (30 mg) once daily for 10 days16 to 23 kg100 mL898 mL7.5 mL (45 mg) twice daily for 5 days7.5 mL (45 mg) once daily for 10 days24 to 40 kg125 mL10123 mL10 mL (60 mg) twice daily for 5 days10 mL (60 mg) once daily for 10 days≥41 kg150 mL12147 mL12.5 mL (75 mg) twice daily for 5 days12.5 mL (75 mg) once daily for 10 daysTable has been converted to the following text.Preparation of Oseltamivir 6 mg/mL Suspension(using water with preservative [ie, 0.05% sodium benzoate]) (Tamiflu Canadian product labeling 2017)Weight-based details:≤15 kg: To make a 6 mg/mL suspension, open six 75 mg capsules. Mix with 74 mL water with preservative to provide a total of 75 mL. Treatment dose is 5 mL (30 mg) twice daily for 5 days.
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