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Author: Admin | 2025-04-28
And was more likely to occur in patients given the 10 mg dose (compared to the 5 and 2.5 mg doses).[Ref]Nervous systemCommon (1% to 10%): Somnolence, dizziness, headacheUncommon (0.1% to 1%): Tremor, taste perversion/dysgeusia, syncope, hypoesthesia, paresthesiaVery rare (less than 0.01%): Hypertonia, peripheral neuropathy, ataxia, migraine, amnesia, parosmiaFrequency not reported: Extrapyramidal syndrome, postural dizziness, vertigo[Ref]Headache occurred commonly during clinical trials, especially at the beginning of treatment.Extrapyramidal syndrome may be associated with this drug.[Ref]GastrointestinalCommon (1% to 10%): Abdominal pain, nauseaUncommon (0.1% to 1%): Vomiting, dyspepsia, altered bowel habits (including diarrhea and constipation), dry mouthVery rare (less than 0.01%): Pancreatitis, gastritis, gingival hyperplasia, loose stoolsFrequency not reported: Dysphagia, flatulence[Ref]DermatologicCommon (1% to 10%): FlushingUncommon (0.1% to 1%): Alopecia, skin discoloration, increased sweating/hyperhidrosis, pruritus, rash, exanthemaVery rare (less than 0.01%): Erythema multiforme, urticaria, exfoliative dermatitis, Stevens-Johnson syndrome, Quincke edema, photosensitivity, skin dryness, cold and clammy skin, dermatitis[Ref]OtherCommon (1% to 10%): FatigueUncommon (0.1% to 1%): Tinnitus, asthenia, pain, malaiseFrequency not reported: Rigors, thirst[Ref]GenitourinaryUncommon (0.1% to 1%): Micturition disorder, nocturia, increased urinary frequency, impotenceVery rare (less than 0.01%): Dysuria, polyuriaFrequency not reported: Male/female sexual dysfunction[Ref]MusculoskeletalUncommon (0.1% to 1%): Arthralgia, myalgia, muscle cramps, back painVery rare (less than 0.01%): Muscle weaknessFrequency not reported: Arthrosis, twitching[Ref]PsychiatricUncommon (0.1% to 1%): Insomnia, mood changes (including anxiety), depressionRare (0.01% to 0.1%): ConfusionFrequency not reported: Abnormal dreams, depersonalization, nervousness, apathy, agitation[Ref]RespiratoryUncommon (0.1% to 1%): Dyspnea, rhinitisVery rare (less than 0.01%): CoughFrequency not reported: Epistaxis[Ref]OcularUncommon (0.1% to 1%): Visual disturbance (including diplopia)Very rare (less than 0.01%): Abnormal visual accommodation, xerophthalmiaFrequency not reported: Abnormal vision, conjunctivitis, eye pain[Ref]MetabolicUncommon (0.1% to 1%): Weight increase/decreaseVery rare (less than 0.01%): Hyperglycemia, increased appetiteFrequency not reported: Anorexia[Ref]HematologicUncommon (0.1% to 1%): PurpuraVery rare (less than 0.01%): Leukopenia, thrombocytopenia[Ref]EndocrineUncommon (0.1% to 1%): Gynecomastia[Ref]HepaticVery rare (less than 0.01%): Hepatitis, jaundice, hepatic enzymes increased[Ref]Increased hepatic enzymes were mostly consistent with cholestasis.Some cases of hepatitis, jaundice, and/or hepatic enzyme elevations were severe enough to require hospitalization; however, the association with this drug was uncertain in most cases.[Ref]HypersensitivityVery rare (less than 0.01%): Allergic reactions, angioedema[Ref]References1. (2002) "Product Information. Norvasc (amlodipine)." Pfizer U.S. Pharmaceuticals2. Cerner Multum, Inc. "UK Summary of Product Characteristics."3. Cerner Multum, Inc. "Australian Product Information."Frequently asked questionsWhat is the best time of day to take blood pressure medication?How do I reduce swelling from amlodipine?How long does it take for amlodipine to work?Does amlodipine cause weight gain?What medications cause swollen ankles and feet?Best time to take amlodipine - day or night?How long does
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