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Author: Admin | 2025-04-28
Uses What Is Amlodipine and How Does It Work? Dosage Dosages of Amlodipine Side Effects What Are Side Effects Associated with Using Amlodipine? Drug Interactions What Other Drugs Interact with Amlodipine? Warnings and Precautions What Are Warnings and Precautions for Amlodipine? What Is Amlodipine and How Does It Work?Amlodipine is a prescription medication that is used with or without other medications to treat high blood pressure. Lowering blood pressure helps prevent strokes, heart attacks, and kidney problems. Amlodipine belongs to a class of drugs known as calcium channel blockers. It works by relaxing blood vessels so blood can flow more easily.Amlodipine is also used to prevent certain types of chest pain (angina). It may help to increase your ability to exercise and decrease the frequency of angina attacks. It should not be used to treat attacks of chest pain when they occur. Use other medications (such as sublingual nitroglycerin) to relieve attacks of chest pain as directed by your doctor.Amlodipine is available under the following different brand names: Norvasc.Dosages of AmlodipineDosages of Amlodipine Should Be Given As Follows:Adult and Pediatric Dosage Forms & StrengthsTablets 2.5 mg 5 mg 10 mgDosage ConsiderationsHypertension (High Blood Pressure)Adult 5 mg/day orally initially; may be increased by 2.5 mg/day every 7-14 days; not to exceed 10 mg/day orally; maintenance: 5-10 mg/day orallyPediatric Children under 6 years: Safety and efficacy not established Children 6 years and older: 2.5-5 mg/day orallyGeriatric 2.5-5 mg/day orally initially; may be increased by 2.5 mg/day every 7-14 days; not to exceed 10 mg/day orally; maintenance: 5-10 mg/day orallyCoronary Artery DiseaseTreatment of chronic stable angina and vasospastic angina (Prinzmetal or variant angina) and angiographically documented coronary artery disease (CAD) in patients without heart failure or ejection fraction (EF) less than 40%Adult 5-10 mg/day orally initially; maintenance: 10 mg/day orallyGeriatric 2.5-10 mg/day orally initially; maintenance: 10 mg/day orallyAnginaAdult 5-10 mg/day orally; maintenance: 10 mg/day orallyGeriatric 2.5-10 mg/day orally; maintenance: 10 mg/dayDosage Modifications Hepatic insufficiency: Consider starting with 2.5 mg/day orally Severe hepatic impairment: Titrate slowlyDosing ConsiderationsAlso given in combination with benazepril (Lotrel), atorvastatin (Caduet), olmesartan (Azor), telmisartan (Twynsta), and valsartan (Exforge)Geriatric Start dosing at the low end of the dosing range; elderly patients have a greater frequency of decreased renal, hepatic or cardiac function What Are Side Effects Associated with Using Amlodipine?Side effects of amlodipine include:Swelling (edema) Excess fluid in the lungs (pulmonary edema) Headache Fatigue Palpitations Dizziness Nausea Flushing Abdominal pain Sleepiness
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