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Author: Admin | 2025-04-28
Your healthcare provider may recommend using anticoagulant medications (blood-thinning medications) to treat or prevent blood clots. Blood-thinning drugs can treat or prevent deep vein thrombosis (DVT, a blood clot, usually in the leg) and pulmonary embolism (PE, a blood clot in the lung), among other conditions stemming from blood clots, in adults. Blood thinners are a crucial form of medication in the United States. To date, more than half of all Americans 18 and older take one or more blood thinners. Notable options include Xarelto (rivaroxaban) and Eliquis (apixaban), two prescription-based, orally administered medications that are categorized as factor Xa inhibitors (drugs that keep your blood from clotting too much). These Food and Drug Administration (FDA)–approved prescription drugs are used to prevent and treat various blood clots. Although both medicines are in the same drug class, they share some distinct differences that potential users should be aware of. Read on for an in-depth analysis of Xarelto vs. Eliquis. Scott Olson / Getty Images The following will outline the purposes for which Xarelto is used, alongside an explanation of how the drug works within the body to create its desired effects. Approved & Off-Label Uses Xarelto is FDA-approved for the following conditions in adults:Lower the risk of stroke and systemic embolism (clots that travel through the circulatory system) in people with nonvalvular atrial fibrillation (AFib, a type of irregular heartbeat that is not caused by a problem with a heart valve)To treat DVTTo treat PETo lower the risk of a DVT or PE from returningTo prevent DVT (which can lead to PE) in individuals who are having knee replacement or hip replacement surgeryTo prevent clots in individuals who are hospitalized and at risk for blood clotsTo lower the risk of cardiovascular (heart) events (heart attack, stroke, or death) in people with coronary artery disease (CAD; damage to the heart's major blood vessels due to plaque build-up)To lower the risk of clotting in people with peripheral artery disease (PAD; poor circulation to the legs due to plaque build-up in the arteries), including individuals after recent lower extremity revascularization (surgery to improve blood flow) Xarelto is FDA-approved for the following conditions in children and adolescents:To treat and lower the risk of clots in people younger than 18To prevent clots in children 2 and older who have congenital heart disease (CAD, a heart condition that develops before birth) following a Fontan procedure, a type of open-heart surgery Sometimes, healthcare providers prescribe an approved drug for a condition or in a manner that is not FDA-approved. This is called off-label prescribing. Healthcare providers sometimes prescribe Xarelto off-label to prevent blood clots after percutaneous coronary intervention (PCI, previously known as angioplasty with a stent). Angioplasty involves
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