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Author: Admin | 2025-04-28
HomeSubutexPatient Tips Medically reviewed by Carmen Pope, BPharm. Last updated on March 14, 2024. How it worksUpsidesDownsidesBottom LineTipsResponse/effectivenessInteractions 1. How it works Subutex was a brand (trade) name for a buprenorphine sublingual product that was available as a tablet and a buccal film. Subutex sublingual tablets were used to treat opioid misuse disorder in adults. Buprenorphine is a partial opioid agonist which means it binds to and activates opioid receptors (particularly mu receptors) but less strongly than full agonists do. This means it can reduce cravings and withdrawal symptoms in a person with an opioid use disorder without producing euphoria. Buprenorphine helps to reduce withdrawal symptoms and curb cravings for opioids by tricking the brain into thinking that a full agonist like oxycodone or heroin has been taken. Some forms of buprenorphine can be used to provide pain relief because activating mu opioid receptors also relieves pain.Subutex belonged to the class of medicines known as narcotic analgesics. It was also called an opioid analgesic. Subutex was only used for the treatment of opioid (narcotic) addiction.Subutex has been discontinued in the U.S. Providers may use Suboxone instead, which contains buprenorphine and naloxone. Other brands of buprenorphine include Belbuca. 2. Upsides Subutex sublingual tablets were used to treat opioid use disorder in adults as part of a complete treatment program that included counseling and psychosocial support, but Subutex is no longer available.Buprenorphine , the ingredient in Subutex, suppresses withdrawal symptoms and cravings for opioids, and also blocks the effects of other opioids for at least 28 days. Buprenorphine is used together with education, counseling, and other support measures that focus on the behavioral aspects of opioid addiction. Subutex sublingual tablets were usually taken as a single daily dose of 4 to 24mg once a day, under the tongue.Generic Subutex is available under the name buprenorphine. 3. Downsides If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: Back pain, cough, chills, a headache, gastrointestinal disorders (eg, constipation, nausea, or vomiting), fatigue, constipation, painful and difficult urination, nasal congestion, and trouble sleeping were the most common side effects reported. Could also cause increases in liver enzymes (eg, alanine aminotransferase, aspartate aminotransferase, gamma-glutamyl transferase), and blood creatine phosphokinase.Allergic reactions (including breathing difficulties, rash, and anaphylactic shock) and liver damage (hepatitis) have been reported. Abuse potential
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