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Author: Admin | 2025-04-28
Interactions As a steroid, prednisone interacts with a long list of drugs and substances. That makes it important for anyone who takes the medication to communicate with doctors the full list of other drugs they take before starting on prednisone.Women who rely on birth control pills with estrogen and take prednisone can experience stronger steroid side effects and potentially less-effective results from their oral contraceptive.Estrogen enhances the effectiveness of prednisone, essentially making it a more potent dose than intended.Patients should tell their health care providers about all the medicines they take and ones they may take. Drug interactions with prednisone include: Oral Birth Control: Drugs with estrogen (birth control pills) may decrease the metabolism of the drug in the liver and increase the effect of corticosteroids. Antibiotics: A certain type of antibiotic called fluoroquinolones can cause damage to tendons. People who take corticosteroids while also taking fluroquinolones, or after taking fluoroquinolones, may be at higher risk for tendon damage. Isoniazid, an antibiotic for tuberculosis, may not work as well when taken with prednisone. Diabetes Drugs: People who take diabetes medications may need increased doses of those because prednisone can increase blood sugar levels. Blood Thinners: Taking warfarin with prednisone may cause the popular blood thinner to not work as well. Have your doctor monitor you closely to make sure warfarin’s anticoagulation effect works while you are on your course of prednisone. Heart Medications: People who are on digoxin, a drug prescribed for heart failure, may be at increased risk of low potassium levels, or hypokalemia. This can lead to heart rhythm issues. Antidepressants: Both bupropion and corticosteroids can make people more susceptible to seizures, so using them together may increase the risk of seizures. Prednisone also may lessen the effect of quetiapine. Higher doses of quetiapine may be needed to
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