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Author: Admin | 2025-04-28
Prevention and treatment of gout and gout flares. The most common effective options for prevention are allopurinol and Uloric (febuxostat), which have similar efficacy rates. The determining factor in deciding which to use can come down to a few factors, such as cost, allergies, or comorbidities. For flares, colchicine is the most common and preferred option. Again, cost, allergies, and other conditions you may have must be considered when prescribing or starting a new medication. Urate-Lowering Drugs Urate-lowering drugs are used to help manage chronic gout and prevent flares. They are recommended for people who have at least two gout flares per year and those with complications like tophi. These medications can be initiated during a flare and will likely need to be taken indefinitely (life-long). This class of drugs includes the following medicines:Allopurinol, which blocks the production of uric acid. This is the preferred medication for chronic gout.Uloric (febuxostat), which also blocks the production of uric acid- but isn't recommended for people with heart disease.Probenecid, which helps the kidneys remove uric acid from the body. This medicine is less effective than allopurinol or Uloric, and it's not recommended for people with a history of kidney stones.Krystexxa (pegloticase) is an intravenous (IV) medicine that breaks down uric acid. This is typically only used if other medicines haven't worked well. Taking either allopurinol or Uloric for six months has been shown to restore normal uric acid levels in the body. But keep in mind that 87% of people who stop taking
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