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Author: Admin | 2025-04-28
Urate-lowering drugs will have a flare within five years. Anti-Inflammatory Medications Anti-inflammatory medications are used short-term to reduce pain and inflammation caused by a gout flare. These medicines include the following:Nonsteroidal anti-inflammatory drugs (NSAIDs) like Motrin (ibuprofen), Aleve (naproxen), or Celebrex (celecoxib). High doses of these medicines are typically needed for three to five days to resolve the flare and prevent another. Your healthcare provider or pharmacist can help you pick the most appropriate NSAID. Of note, all the drugs in this class may raise blood pressure and can increase the risk of heart failure.Corticosteroids, such as prednisone, which can be injected into the joint or taken by mouth. As with NSAIDs, short courses are used to minimize side effects. Adverse effects of steroids include trouble sleeping, anxiety, and weight gain.Colcrys (colchicine) is most effective when started at the first symptoms of a gout flare. Colchicine may need to be dosed lower for people with chronic kidney disease (CKD) and those who take some medications, such as statins. Be sure to run your medication list by your healthcare provider or pharmacist to be safe. In contrast to NSAIDs and corticosteroids, colchicine may be continued long-term to prevent recurrent flares. Other options include adrenocorticotropic hormone (ACTH)and interleukin-1 inhibitors such as the following: Ilaris (canakinumab)Kineret (anakinra)Arkalyst (rilonacept) and ACTH These medications are expensive, and there's not enough research to know how effective they are for gout. They're not typically used unless standard treatments haven't worked. Pain Relief at Home Some simple strategies
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