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Author: Admin | 2025-04-28
Brand NamesAdcircaCialis Drug ClassA phosphodiesterase 5 (PDE5) inhibitor IndicationsTreatment of erectile dysfunction (ED) (Cialis)Treatment of the signs and symptoms of benign prostatic hyperplasia (BPH) (Cialis) Treatment of ED and the signs and symptoms of BPH (ED/BPH) (Cialis) Treatment of pulmonary arterial hypertension (WHO Group 1) to improve exercise ability (Adcirca) Dosing (Adult)General Dosing & Administration Notes: If used with finasteride to initiate BPH treatment, such use if recommended for up to 26 weeks. May be taken without regard to food. Do not split tablets; entire dose should be taken. Once-daily use: take at approximately the same time every day (Cialis). Dividing the dose (40 mg) over the course of the day is not recommended (Adcirca) Erectile Dysfunction (ED): As needed use: 10 mg by mouth prior to sexual activity. May increase to 20 mg or decrease to 5 mg, based on individual efficacy and tolerability. Maximum dosing frequency: once daily Once-daily use: 2.5 mg once daily. May increase to 5 mg once daily based on individual efficacy and tolerability Benign Prostatic Hyperplasia (BPH; +/- Erectile Dysfunction): 5 mg by mouth once daily Note: If initiated with finasteride: 5 mg by mouth once daily for ≤ 26 weeks Pulmonary Arterial Hypertension (PAH; WHO Group 1):40 mg (two 20 mg tablets) by mouth once daily Renal DosingAdcirca: Mild (CrCl 51-80 mL/min) or Moderate (CrCl 31-50 mL/min):20 mg once dailyIncrease to 40 mg once daily based on individual tolerability Adcirca: Severe (CrCl :Avoid useCialis: PRN use, CrCl 30-50 mL/min: 5 mg once dailyMax Dose: 10 mg/48 hoursCialis: PRN use, CrCl : Max Dose: 5 mg/72 hoursCialis: once-daily use, ED, CrCl :Not recommendedCialis: once-daily use, BPH or ED/BPH, CrCl 30-50 mL/min: 2.5 mg; may increase to 5 mg based on individual responseCialis: once-daily use, BPH or ED/BPH, CrCl : Not recommended Hepatic DosingAdcirca, mild
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