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Author: Admin | 2025-04-28
Disorders. To achieve the desired effect for conditions like OCD, PD, PTSD, SAD, and PMDD, the dosage would need to be increased beyond the limit of tolerability, outweighing the potential benefits. Here is the list of side effects affecting 5% or more of Lexapro and Zoloft users (by order of frequency): LexaproNauseaInsomniaEjaculation problemsDiarrheaInsomniaDry mouthDrowsinessFlu-like symptomsFatigueRunny, stuffy noseDizzinessIncreased sweatingZoloftNauseaDiarrheaInsomniaDry mouthDizzinessFatigueDrowsinessTremorsAgitationEjaculation problemsUpset stomachDecreased appetiteConstipationLow sex drive Interactions and Warnings Because of their mechanism of action, both Lexapro and Zoloft cause similar drug interactions and carry similar health warnings. Among them, the FDA has issued black box warnings advising consumers that antidepressants like Lexapro and Zoloft increase the risk of suicidal thoughts and behaviors in children and young adults. Lexapro and Zoloft can both interact with drugs that use CYP2D6 for metabolization. Taking them together can cause the drugs to "compete" for the available enzyme, causing drug concentrations to fall or rise. If concentrations decrease, the drug will become less effective; if concentrations rise, it can increase the risk of side effects and lead to toxicity. Common drug interactions include:Dilantin (phenytoin)Lanoxin (digoxin)LithiumTagamet (cimetidine)Tegretol (carbamazepine)Tenormin (atenolol)Valium (diazepam)Orap (pimozide) Other drugs can also interact with Lexapro and Zoloft, so advise your healthcare provider of any medications you take before starting treatment. In some cases, a dose adjustment or drug substitution may be needed. At other times, separating the dose by several hours will be all that is needed to overcome the interaction. Cost The wholesale acquisition cost (WAC) of Lexapro is roughly $1,300 per month, while the WAC for Zoloft is closer to $400 per month. This difference is due in part to the fact that Zoloft is an older drug first licensed by the FDA in 1991, while Lexapro received licensing in 2002. With that said, the WAC does not reflect the price you
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