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Author: Admin | 2025-04-28
Uses What Is Diethylcarbamazine Used For and How Does it Work? Dosage What Are Dosages of Diethylcarbamazine? Side Effects What Are Side Effects Associated with Using Diethylcarbamazine? Drug Interactions What Other Drugs Interact with Diethylcarbamazine? Warnings and Precautions What Are Warnings and Precautions for Diethylcarbamazine? What Is Diethylcarbamazine Used For and How Does it Work?Diethylcarbamazine is used to treat certain parasitic diseases caused by infection with roundworms of the Filarioidea type, including lymphatic filariasis caused by infection with Wuchereria bancrofti, Brugia malayi, or Brugia timori; tropical pulmonary eosinophilia; and loiasis.Diethylcarbamazine is not commercially available in the U.S.Diethylcarbamazine is available under the following different brand names: Hetrazan.What Are Dosages of Diethylcarbamazine?Dosages of Diethylcarbamazine: Not commercially available in the U.S. Diethylcarbamazine is available from the Centers for Disease Control (CDC) Drug Service for patients via an investigational new drug (IND) protocol for treatment of certain filarial diseases, including lymphatic filariasis caused by infection with Wuchereria bancrofti, Brugia malayi, or Brugia timori; tropical pulmonary eosinophilia; and loiasis It is also available for prophylactic use in persons determined to be at increased risk for Loa loa infectionDosage Considerations – Should be Given as Follows:Filarial DiseasesIND protocol from CDC available for treatment of certain filarial diseases, including lymphatic filariasis caused by infection with Wuchereria bancrofti, Brugia malayi, or Brugia timori. 2-4 g/day orallyAdult: Day 1: 50 mg orally after meals Day 2: 50 mg orally three times daily Day 3: 100 mg orally three times daily Day 4-14: 6 mg/kg/day orally divided three times dailyPediatric: Day 1: 1 mg/kg orally after meals Day 2: 1 mg/kg orally three times daily Day 3: 1-2 mg/kg orally three times daily Day 4-14: 6 mg/kg/day orally divided three times dailyLoa LoaAdult Day 1: 50 mg orally after meals Day 2: 50 mg orally three times daily Day 3: 100 mg orally three times daily Day 4-21: 9 mg/kg/day orally divided three times dailyM. Streptocerca 6 mg/kg orally once daily for 14 daysTropical Pulmonary Eosinophilia - Adult and Pediatric IND protocol from CDC available for treatment of tropical pulmonary eosinophilia Pulmonary eosinophilia, tropical: 6 mg/kg/day divided three times daily for 14 daysLarva Migrans, Visceral - Adult and Pediatric 6 mg/kg/day orally divided three times daily for 7-10 days What Are Side Effects Associated with Using Diethylcarbamazine?Common side effects of diethylcarbamazine include:FeverGI disturbancesRare side effects of diethylcarbamazine include:Brain disease (encephalopathy)This document does not contain all possible side effects and others
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