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Author: Admin | 2025-04-28
At room temperature.Nahata MC, Pai VB, and Hipple TF, Pediatric Drug Formulations, 5th ed, Cincinnati, OH: Harvey Whitney Books Co, 2004.AdministrationOral:Immediate release: May administer without regards to meals. Administer first dose on first day at bedtime to avoid somnolence and dizziness. Dosage must be adjusted for renal function; when given 3 times daily, the maximum time between doses should not exceed 12 hours. Capsules may be opened and sprinkled on food (eg, applesauce, orange juice, pudding) for patients unable to swallow capsules (Gidal 1998).Extended release: Administer with evening meal. Swallow whole; do not chew, crush, or split. Dietary ConsiderationsExtended release tablet should be taken with food. StorageCapsules and tablets: Store at 25°C (77°F); excursions permitted to 15°C to 30°C (59°F to 86°F). Use scored 600 or 800 mg tablets that are broken in half within 28 days of breaking the tablet.Oral solution: Store refrigerated at 2°C to 8°C (36°F to 46°F). Gabapentin Images gabapentin 800 mg gabapentin 300 mg gabapentin 400 mg gabapentin 300 mg gabapentin 100 mg gabapentin 600 mg Drug InteractionsAlcohol (Ethyl): CNS Depressants may enhance the CNS depressant effect of Alcohol (Ethyl). Monitor therapyAlizapride: May enhance the CNS depressant effect of CNS Depressants. Monitor therapyAluminum Hydroxide: May decrease the serum concentration of Gabapentin. Management: Administer gabapentin at least 2 hours after administration of antacids containing aluminum hydroxide or magnesium hydroxide. Consider therapy modificationAzelastine (Nasal): CNS Depressants may enhance the CNS depressant effect of Azelastine (Nasal). Avoid combinationBlonanserin: CNS Depressants may enhance the CNS depressant effect of Blonanserin.
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