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Author: Admin | 2025-04-28
Abilify (Aripiprazole) is a medication that was developed by Otsuka Pharmaceuticals and approved by the FDA in 2002 for the treatment of schizophrenia. Approximately 2 years thereafter (in 2004) it was approved for the treatment of acute mania and mixed episodes associated with bipolar disorder. By 2007, it had attained approval for the treatment of major depression as an adjunct (“add-on”) intervention when prescribed with a traditional antidepressant.As a result of its approval to treat an array of psychiatric conditions, it emerged as among the top selling psychiatric drugs from 2013 to 2014. The drug functions primarily as a D2 receptor partial agonist, thereby modulating dopamine concentrations in the brain to combat positive and negative symptoms of schizophrenia, as well as acute mania. It also affects the serotonergic system to elevate mood via acting as a 5-HT1A receptor partial agonist, as well as a 5-HT7 receptor and 5-HT2C receptor agonist.Though many people have had success with this drug, others have a difficult time tolerating Abilify side effects such as: agitation, constipation, headaches, insomnia, nausea, etc. Others may be upset that they’re gaining weight while taking Abilify or could be concerned with long-term health implications of using atypical antipsychotics. For these reasons, many individuals have ceased usage of Abilify and may be wondering how long it stays in their system after stopping.If you’ve recently stopped taking this medication, you may be dealing with debilitating Abilify withdrawal symptoms. As you attempt to cope with these discontinuation symptoms, you’re probably wondering how long the Abilify, or more specifically the active ingredient “Aripiprazole” will remain in your body. To understand how long Abilify remains in your system after you stop taking it, it is necessary to examine its elimination half-life.The elimination half-life of Aripiprazole is generally considered to fall within the range of 75
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