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Author: Admin | 2025-04-28
Introduction to Pharmaceutical Dosage Form Drugs are rarely delivered as pure chemical entities but are approximately usually provided as prepared formulations i.e. dosage form. After converting them into an appropriate dose formulation, they are delivered in several dosage forms.To create an alternative dosage form, non-medicinal chemicals (also known as pharmaceutical ingredients or excipients) are added. By adding pharmaceutical ingredients that solubilize or suspend or thicken or dilute or emulsify or stabilize or preserve them, drug dosage forms can be made more effective and appealing. Definition of Dosage Form Dosage forms are the mechanism by which drug molecules / APIs are administered to areas of action inside the body to generate maximum intended benefits and the lowest unwanted effects. OR The Dosage form is the combination of Active Pharmaceutical Ingredients (API) and Excipients in the formulation. Need of Dosage Forms Mainly depend on Patient Safety and Drug Safety/ Benefits. 1. Deliver precise dosages in a safe and easy manner. Example – Tablets, capsules, syrups 2. Cover bitter taste or odor of drug substances. Example – Capsules, coated tablets, flavored syrups 3. Insoluble or unstable in the selected vehicle, provide a liquid formulation of the insoluble or unstable medication. Example – Suspension 4. Controlled-release methods prolong the duration of medication effect. Example – Controlled release tablets, capsules, suspensions 5. After oral delivery, a drug substance is protected from stomach acid. Example – Enteric-coated tablets 6. Provide optional drug action from topical administration sites. Example – Ointment, cream, ear and nasal preparations 7. Drugs can be injected into the body's tissues. Example – Implants 8. Inhalation treatment is the most effective way to get optimum medication activity. Example – Inhalants 9. Liquid dosage forms of chemicals soluble in the vehicle of your choice. Example – Solution 10. Provide for the introduction of medication into the body’s orifice. Example – Rectal and vag*inal suppositories 11. Protection of a drug substance from atmospheric oxygen or moisture. Example – Coated capsules, sealed ampules. Definition of Drug (Active Pharmaceutical Ingredients) Drogue is an old French term that means "dry herb" and is sometimes used interchangeably with the
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