Comment
Author: Admin | 2025-04-28
And Adolescents: IV, Oral: 30 mg/kg/day in divided doses 4 times daily for 7 to 10 days; maximum daily dose: 4,000 mg/day (Red Book [AAP 2018])Trichomoniasis; treatment: Oral:Children day in divided doses 3 times daily for 7 days; maximum daily dose: 2,000 mg/day (Red Book [AAP 2018])Children ≥45 kg and Adolescents: 2,000 mg as a single dose once or 500 mg twice daily for 7 days (CDC [Workowski 2015]; Red Book [AAP 2018])Vaginosis, bacterial: Oral: Children >45 kg and Adolescents: 500 mg twice daily for 7 days (CDC [Workowski 2015]; Red Book [AAP 2018])Extemporaneously PreparedNote: A metronidazole suspension (50 mg/mL or 100 mg/mL) is commercially available as a compounding kit.50 mg/mL Oral Suspension (ASHP Standard Concentration) (ASHP 2017)A 50 mg/mL oral suspension may be made with tablets and a 1:1 mixture of Ora-Sweet and Ora-Plus. Crush twenty-four 250 mg tablets in a mortar and reduce to a fine powder. Add small portions of the vehicle and mix to a uniform paste; mix while adding the vehicle in incremental portions to almost 120 mL; transfer to a calibrated bottle, rinse mortar with vehicle, and add quantity of vehicle sufficient to make 120 mL. Label "shake well". Stable for 60 days at room temperature or refrigerated (Allen 1996).Allen LV Jr, Erickson MA 3rd. Stability of ketoconazole, metolazone, metronidazole, procainamide hydrochloride, and spironolactone in extemporaneously compounded oral liquids. Am J Health Syst Pharm. 1996;53(17):2073-2078.8870895AdministrationIV: Infuse intravenously over 30 to 60 minutes. Avoid contact of drug solution with equipment containing aluminum.Oral: Administer with food to minimize stomach upset. Dietary ConsiderationsTake with food to minimize stomach upset.Sodium: Injectable dosage form may contain sodium.Ethanol: Use of ethanol is contraindicated during therapy and for 3 days after therapy discontinuation. StorageOral: Store at 15°C to 25°C (59°F to 77°F). Protect the tablets from light.Injection: Store at 20°C to 25°C (68°F to 77°F). Protect from light. Avoid excessive heat. Do not refrigerate. Do not remove unit from overwrap until ready for use. Discard unused solution. MetroNIDAZOLE (Systemic) Images metronidazole 250 mg metronidazole 500 mg metronidazole 500 mg metronidazole 500 mg metronidazole 250 mg metronidazole 500 mg Drug InteractionsAlcohol (Ethyl):
Add Comment