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Author: Admin | 2025-04-28
Ultram)Sedative-hypnotic drugs, such as:ramelteon (Rozerem)zaleplon (Sonata)zolpidem (Ambien)Benadryl and XanaxXanax (alprazolam) is a type of drug called a benzodiazepine, which can cause sleepiness. Taking Xanax with Benadryl can increase your risk of excessive sleepiness. This can make you too sleepy to drive or prevent you from doing other potentially dangerous activities safely.If you take Xanax, talk with your doctor before taking Benadryl. They may recommend other treatment options.Benadryl and ZoloftZoloft (sertraline) is an antidepressant that can cause sleepiness in some people. Taking Zoloft with Benadryl may increase the risk of excessive sleepiness. This can make you too sleepy to drive or prevent you from doing other potentially dangerous activities safely.If you take Zoloft, talk with your doctor before taking Benadryl. They may recommend other treatment options.Benadryl and ZyrtecZyrtec (cetirizine) is an antihistamine. Benadryl is also an antihistamine. Taking Benadryl with Zyrtec may increase the risk of certain side effects such as sleepiness, dry mouth, fatigue, and headache.If you take Zyrtec, talk with your doctor before taking Benadryl. They may recommend other treatment options.Benadryl and MotrinThere are no known interactions between Benadryl and Motrin (ibuprofen).Benadryl and acetaminophenThere are no known interactions between Benadryl and acetaminophen (Tylenol).Benadryl and herbs and supplementsSome herbs and supplements can cause sleepiness. Taking these with Benadryl can increase the risk of excessive sleepiness. Examples of these supplements include:chamomilekavamelatoninvalerianTake or apply Benadryl according to the instructions on the package or according to the directions you’ve received from your doctor.TimingFor hay fever or other respiratory allergies, you typically take oral Benadryl every 4 to 6 hours. If you use topical Benadryl to treat itchy skin, you will apply it up to four times daily. You should separate each application by 4 to 6 hours.Taking Benadryl with foodYou can take Benadryl with or without food.Can Benadryl be crushed?You can crush Benadryl tablets. If you have difficulty swallowing whole tablets, Benadryl liquid solution and chewable tablets are available.Benadryl is an antihistamine. If you have allergies or have a cold, your body releases a chemical messenger called histamine. Histamine causes symptoms such as inflammation, edema (swelling), itchiness, and a runny nose.Benadryl blocks some of the effects of histamine and decreases some of the symptoms it causes.How long does it take to work?When you take Benadryl by mouth, it begins to work within 15 to 30 minutes. When you apply it to your skin, it works right away.Here are answers to some frequently asked
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