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Author: Admin | 2025-04-28
Et al; for the SURPASS-2 Investigators. Tirzepatide versus semaglutide once weekly in patients with type 2 diabetes. N Engl J Med. 2021;385(6)(suppl):503-515. doi: 10.1056/NEJMoa2107519Karagiannis T, Avgerinos I, Liakos A, et al. Management of type 2 diabetes with the dual GIP/GLP-1 receptor agonist tirzepatide: a systematic review and meta-analysis. Diabetologia. 2022 Aug;65(8):1251-1261. doi: 10.1007/s00125-022-05715-4Azuri J, Hammerman A, Aboalhasan et al. Tirzepatide versus semaglutide for weight loss in patients with type 2 diabetes mellitus: A value for money analysis. Diabetes Obes Metab.2023;25:961–964Pharmacologic Approaches to Glycemic Treatment: Standards of Care in Diabetes-2024. American Diabetes Association Professional Practice Committee . Diabetes Care. 2024;47(Suppl 1):S158 https://diabetesjournals.org/care/article/47/Supplement_1/S158/153955/9-Pharmacologic-Approaches-to-Glycemic-TreatmentOzempic prescribing information. Revised 9/2023. Novo Nordisk. Plainsboro, NJ. https://www.novo-pi.com/ozempic.pdfZepbound (tirzepatide) prescribing information. Nov. 2023. Eli Lilly. Indianapolis, IN https://uspl.lilly.com/zepbound/zepbound.html#piMounjaro (tirzepatide) prescribing information. July 2023. Eli Lilly. Indianapolis, IN. at https://uspl.lilly.com/mounjaro/mounjaro.html#piWegovy (semaglutide) prescribing information. July 2023. NovoNordisk. Plainsboro, NJ at https://www.novo-pi.com/wegovy.pdfRybelsus [package insert]. Plainsboro, NJ: Novo Nordisk Inc; Revised 1/2024 at https://www.novo-pi.com/rybelsus.pdf Read next Why am I not losing weight on Ozempic? Although Ozempic is not FDA-approved for weight loss, over 86% of people lose at least 5% of their body weight in trials that have studied semaglutide, the active ingredient of Ozempic. But the same clinical trials also show that just under 14% don’t lose weight, and some may even gain weight. Continue reading Where and how should Ozempic be injected? Ozempic (generic name: semaglutide) is a pen prefilled with an injectable medicine given by self-injection once a week, on the same day each week, with or without meals. Ozempic is injected under the skin (subcutaneously) in your stomach (abdomen), thigh, or upper arm area. Continue reading How much does semaglutide cost? Semaglutide (Wegovy) injection for weight loss treatment costs about $1418 per month if you are paying cash without insurance or manufacturer's copay cards. Semaglutide for treatment of type 2 diabetes costs $1051 per month for either the Ozempic pen injection or 30 oral tablets of Rybelsus. Continue reading Related medical questions Does Ozempic cause muscle loss and how to prevent it? How does Ozempic affect blood pressure? What foods should I eat or avoid when taking Rybelsus? Ozempic Face: What causes it and how to prevent it? How much weight can you lose with Rybelsus? Trulicity vs Ozempic: Which is right for you? Why does Ozempic cause a dry mouth or taste changes? How long does it take for Rybelsus to start working? Can you just stop taking Rybelsus? Does Wegovy make you pee a lot or urine smell? What is compounded semaglutide and is it safe? How does Wegovy work for weight loss? Can I drink alcohol on Ozempic? Can Wegovy or Ozempic be used for heart failure? What is the mechanism of action for Rybelsus?
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