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Author: Admin | 2025-04-28
10%): Injection site pain[Ref]CardiovascularCommon (1% to 10%): Arterial thromboembolic events[Ref]Intravitreal use of VEGF inhibitors has been associated with a potential risk of arterial thromboembolic events (ATEs) defined as nonfatal stroke, nonfatal myocardial infarction, or vascular death (including death of unknown cause). In wet age-related macular degeneration (AMD) studies, 1.8% (n=32/1824) and 1.5% (n=9/595) of patients treated with this drug or ranibizumab, respectively, experienced an ATE in the first 52 weeks and 3.3% and 3.2% through 96 weeks, respectively. In the diabetic macular edema (DME) studies, ATEs were reported at incidences of 3.3% (n=19/578) and 2.8% (n=8/287) through week 52, and 6.4% (n=37/578) and 4.2% (n=12/287) through week 100, in patients receiving 2 different dosing regimens of this drug or macular laser photocoagulation (after the first 24 weeks, all patients could receive drug or laser treatment). No ATEs have been reported in the first 6 months of the retinal vein occlusion (RVO) studies.[Ref]HypersensitivityUncommon (0.1% to 1%): HypersensitivityReferences1. Cerner Multum, Inc. "UK Summary of Product Characteristics."2. Cerner Multum, Inc. "Australian Product Information."3. (2011) "Product Information. Eylea (aflibercept ophthalmic)." Regeneron Pharmaceuticals IncFrequently asked questionsWhat is the difference between Vabysmo and Eylea?What’s the difference between Eylea, Eylea HD, and Avastin?What are anti-VEGF drugs (VEGF inhibitors)?How long does Eylea or Eylea HD take to work?Does Medicare cover Eylea injections?What is the difference between Eylea and Eylea HD?Does Eylea and Eylea HD raise blood pressure?When do the Eylea and Eylea HD patents expire?Does Eylea have a biosimilar?Further informationEylea side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.Medical Disclaimer
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