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Author: Admin | 2025-04-28
Shortage is completely over, the FDA will list them as “resolved” and remove them from the shortage list. This was done earlier this month for Mounjaro and Zepbound (Eli Lilly) as the supply now exceeds demand.Ozempic and Wegovy both contain semaglutide, while Mounjaro and Zepbound contain tirzepatide. Ozempic and Mounjaro are both FDA-approved to treat patients with type 2 diabetes, and Wegovy and Zepbound are approved for weight loss.Honorable Mention: IV FluidsEarlier this month, the FDA added Dextrose 70% intravenous (IV) solution, Peritoneal Dialysis Solution, and Lactated Ringers IV Solution to the Drug Shortage Database.10 This is because of Hurricane Helene’s impact on a Baxter manufacturing plant, which produces over 60% of large-volume IV fluids in the US.11 As a result, Baxter products are not available in adequate supply to meet the current demand.Given the shortage, the FDA released guidance that allows temporary flexibility for compounding these drugs without patient-specific prescriptions.10 It urges careful patient tracking for compounded drug-related issues and encourages reporting adverse events.If supplies dwindle, additional drugs could be added to the shortage list. The FDA also acknowledged concerns about expired IV fluids, clarifying that extending expiration dates requires manufacturer stability data; as of October 18, no such data has been received to support an extension.ReferencesNational drug shortages: January 2001 to September 2024. ASHP. Accessed October 31, 2024. https://www.ashp.org/drug-shortages/shortage-resources/drug-shortages-statisticsPourmahram T. Collaborative solutions are needed to address and mitigate America’s drug shortages. AJMC. June 17, 2024. Accessed October 31, 2024. https://www.ajmc.com/view/collaborative-solutions-are-needed-to-address-and-mitigate-america-s-drug-shortagesFDA Drug Shortages. FDA. Accessed October 31, 2024. https://dps.fda.gov/drugshortagesDurbin K. Adderall. Drugs.com. Updated August 23, 2023. Accessed October 31, 2024. https://www.drugs.com/adderall.htmlLisdexamfetamine dimesylate (oral route). Mayo Clinic. Updated February 1, 2024. Accessed October 31, 2024. https://www.mayoclinic.org/drugs-supplements/lisdexamfetamine-dimesylate-oral-route/description/drg-20070888Keenan J. FDA commissioner heralds end to US shortfall of chemo drug cisplatin. Fierce Pharma. July 1, 2024. Accessed October 31, 2024. https://www.fiercepharma.com/manufacturing/fda-heralds-end-us-shortfall-chemo-drug-cisplatinAlltucker K. As insulin shortages persist, what diabetes patients can do. USA Today. October 24, 2024. Accessed October 31, 2024. https://www.usatoday.com/story/news/health/2024/10/24/insulin-shortage-2024-ozempic-diabetes/75821654007/Insulin detemir injection. ASHP. Updated September 22, 2024. Accessed October 31, 2024. https://www.ashp.org/drug-shortages/current-shortages/drug-shortage-detail.aspx?id=1006Kindelan K. Ozempic, Wegovy move closer to no longer being in shortage, FDA says. ABC News. October 30, 2024. Accessed October 31, 2024. https://abcnews.go.com/GMA/Wellness/ozempic-wegovy-move-closer-longer-shortage-fda/story?id=115321505Gallagher A. FDA adds intravenous fluids to list of drug shortages. Pharmacy Times. October 18, 2024. Accessed October 31, 2024. https://www.pharmacytimes.com/view/fda-adds-intravenous-fluids-to-list-of-drug-shortagesNavigating IV fluid shortages post-Hurricane Helene: insights from USP on compounding and conservation strategies. Pharmacy Times. October 24, 2024. Accessed October 31, 2024. https://www.pharmacytimes.com/view/navigating-iv-fluid-shortages-post-hurricane-helene-insights-from-usp-on-compounding-and-conservation-strategies
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