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Author: Admin | 2025-04-28
But, like all stimulant medications, Vyvanse is a federally-controlled substance due to its addictive nature and risk of dependence. This means when and how it’s prescribed, and who it’s prescribed by, is government-regulated.On the other hand, as an NDRI, Wellbutrin is an atypical antidepressant. This means it’s often used when more traditional antidepressants have failed. Like Vyvanse, it increases the amount of norepinephrine and dopamine in the brain. But, instead of increasing the production of these neurotransmitters, Wellbutrin prevents what’s already there from being taken back into your brain cells. So, there’s more norepinephrine and dopamine available for the brain to use. Overall, this leads to a more balanced mood and improves symptoms of depression. What conditions do Wellbutrin and Vyvanse treat?The U.S. Food and Drug Administration (FDA) approves medications for specific uses. If a medication is prescribed for an unapproved use, it’s considered off-label prescribing. Here we cover Vyvanse and Wellbutrin’s approved uses, and what they can be prescribed off-label for. Conditions Vyvanse treatsVyvanse is FDA-approved to treat symptoms of ADHD in people older than 6 years. And, it’s sometimes prescribed off-label for treatment-resistant depression. Vyvanse is proven effective in treating the core symptoms of ADHD— inattention, hyperactivity, and impulsivity. Studies show it also improves executive functioning, or the mental processes needed to set and achieve goals, solve problems, and regulate emotions. Because emotional dysregulation in ADHD is common, Vyvanse proves an effective ADHD treatment that’s mostly comprehensive (therapy may also be needed).Conditions treated by Wellbutrin Wellbutrin is approved by the FDA to treat major depressive disorder (MDD). Its extended-release formula is also approved to treat seasonal affective disorder (SAD). Off-label uses for Wellbutrin include:ADHDAntidepressant-induced sexual dysfunctionDepression associated with bipolar disorderObesitySmoking cessationWellbutrin may also be helpful for OCD and anxiety that often present with symptoms of depression. How it treats depression symptoms isn’t fully understood, but studies show it’s effective. In a review of Wellbutrin trials, depression scores improved in 24 out of 27 studies.How do Vyvanse and Wellbutrin work together?Though they use different mechanisms, Vyvanse and Wellbutrin increase the available amounts of neurotransmitters norepinephrine and dopamine in the brain. Because of this, Vyvanse and Wellbutrin have a synergistic (cooperative) effect when used to treat ADHD and depression. ADHD is often comorbid with other mental health conditions, including many varieties of depression, like SAD. These 2 medications may be suitable for people who have ADHD and comorbid depression. But, taking the Vyvanse and Wellbutrin together increases the risk of certain side effects.Here’s a breakdown of the potential benefits and drawbacks.Benefits of taking Vyvanse and Wellbutrin togetherVyvanse and Wellbutrin may be prescribed together to help treat ADHD and depression in people who have both conditions.The 2 medications may have complementary
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