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Author: Admin | 2025-04-28
Uses What Is Hydroxyzine and How Does It Work? Dosage What Are the Dosages of Hydroxyzine? Side Effects What Are Side Effects Associated with Using Hydroxyzine? Drug Interactions What Other Drugs Interact with Hydroxyzine ? Warnings and Precautions What Are Warnings and Precautions for Hydroxyzine ? What Is Hydroxyzine and How Does It Work?Hydroxyzine is used for the short-term treatment of nervousness and tension that may occur with certain mental/mood disorders (e.g., anxiety, dementia). It is also used to help manage withdrawal symptoms (e.g., anxiety, agitation) in alcoholics.Other uses include helping to decrease anxiety and nausea before/after surgery or during childbirth or helping certain narcotic pain relievers (e.g., meperidine) work better. Hydroxyzine belongs to a class of medications called antihistamines. It is thought to work by affecting certain natural substances (acetylcholine, serotonin) in your body or by acting directly on certain parts of the brain. Hydroxyzine also blocks a natural substance that your body makes during an allergic reaction (histamine). Hydroxyzine is available under the following different brand names: Vistaril.What Are the Dosages of Hydroxyzine?Dosages of Hydroxyzine:Adult Dosage Forms and StrengthsTablet 5 mg 25 mg 50 mgCapsule 25 mg 50 mg 100 mgSyrup/oral suspension 10 mg/5mLInjectable solution 25 mg/5mL 50 mg/5mLDosage Considerations – Should be Given as Follows:Anxiety Symptomatic relief of anxiety associated with psychoneurosis and as an adjunct in organic disease states 50-100 mg orally divided every 6 hours or 50-100 mg intramuscularly (IM) divided every 4-6 hours Younger than 6 years old: 50 mg/day orally divided every 6 hours Children 6 years of age and older: 50-100 mg/day orally divided every 6 hours Geriatric: 50-100 mg orally divided every 6 hours or 50-100 mg IM divided every 4-6 hours Dosing considerations Continuation of therapy for more than 4 months has not been studied; reassess the need for therapy periodically Pruritus (Itching) Management of pruritus due to chronic hives (urticaria), contact dermatoses, and histamine-mediated pruritus 25 mg oral/intramuscular (IM) divided every 6-8 hours Younger than 6 years old: 50 mg/day orally divided every 6 hours Children 6 years of age and older: 50-100 mg/day orally divided every 6 hours Geriatric: 25 mg oral/IM every 6-8 hours; increased to 25 mg every 6-8 hoursPreoperative Sedation Adult: 50-100 mg orally or 25-100 mg intramuscularly (IM) Pediatric: 0.6 mg/kg orally, or 0.5-1.1 mg/kg IM Dosing considerations If treatment is initiated IM, subsequent doses may be administered orally Dose ModificationRenal Impairment Greater than 50 mL/min: Dose adjustment not necessary 50 mL/min or more: Administer 50% normal doseHepatic Impairment Change dosing interval to every 24 hours in patients with biliary cirrhosisGeriatric Advanced age associated with reduced drug clearance and with greater risk of confusion, dry mouth, constipation, and other anticholinergic effects and toxicity; start at the low end of the dosage range, and observe closely What Are Side Effects Associated with Using Hydroxyzine?Side effects associated with use of Hydroxyzine, include the following: Dry mouthDrowsiness (usually transitory and may disappear in a few days of continued therapy or upon reduction of the dose)Involuntary motor activity
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